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Home / News / Oncology News

ONCOLOGY NEWSFEED

FDA Approves Rucaparib for Recurrent Ovarian, Fallopian Tube, Peritoneal Cancer

April 6, 2018

On April 6, 2018, the Food and Drug Administration approved rucaparib (Rubraca, Clovis Oncology Inc.), a poly ADP-ribose polymerase (PARP) inhibitor, for the maintenance treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.

Read the FDA announcement here.


CMS Begins Mailing Out New Medicare Cards

April 4, 2018

The Centers for Medicare & Medicaid Services (CMS) has begun mailing its newly-designed Medicare cards with new Medicare Beneficiary Identifiers to newly eligible and current Medicare beneficiaries. Cards will be sent out on a rolling basis throughout 2018 to fulfill the CMS requirement to remove Social Security Numbers from all Medicare cards by April 2019.

CMS will host a special Open Door Forum on April 5, 12:30 – 1:30 PM EST, to share updates about the new Medicare card mailing, information on how people with Medicare can look up their new Medicare card number or print a replacement card, and updates on resources for partners. To participate, visit https://webinar.cms.hhs.gov/r51uia09fgq/ and use the following information:

  • Dial-In Number: 1-800-837-1935
  • Conference ID #: 7065199

Check cms.gov/newcard often for the most up-to-date information.

Posted 4/4/2018


ASTRO Updates Guideline for Palliative Lung Radiation

April 4, 2018

On April 4, the American Society for Radiation Oncology (ASTRO) issued an update to its clinical guideline for the use of palliative-intent radiation therapy for patients with incurable non-small cell lung cancer (NSCLC). The updated guideline now recommends the addition of concurrent chemotherapy to radiation therapy for certain patients with incurable stage III NSCLC that are able to tolerate chemotherapy and have a longer life expectancy than three months, reflecting new evidence gathered from randomized clinical trials.

Read the press release from ASTRO here.

Posted 4/4/2018


CMS Issues Final Rule on CY2019 Policy Changes and Updates to MA, Part D

April 3, 2018

On April 2, 2018, the Centers for Medicare & Medicaid Services (CMS) issued a final rule to update Medicare Advantage (MA) and the Part D prescription drug benefit program. Included in the final rule, among additional changes, are:

  • Codifying the methodology of Star Ratings for Part C and D programs
  • Revising regulations that control maximum out-of-pocket and cost-sharing limits
  • Limiting the Part D special enrollment period for dual or other LIS-eligible beneficiaries
  • Changing the Medicare Advantage open enrollment period

Read a CMS fact sheet that provides details on the major provisions of the final rule.


Posted 4/3/2018


FDA Approves Blinatumomab for B-Cell Precursor ALL with MRD

March 29, 2018

On March 29, 2018, the U.S. Food and Drug Administration (FDA) granted accelerated approval to blinatumomab (Blincyto, Amgen Inc.) for the treatment of adult and pediatric patients with B-cell precursor acute lymphoblastic leukemia (ALL) in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1%. Read FDA announcement .

Posted 3/29/2018


CMS Extends MIPS 2017 Data Submission Deadline to April 3

March 29, 2018

The Centers for Medicare & Medicaid Services has announced that eligible clinicians participating in the Quality Payment Program (QPP) now have until Tuesday,April 3, 2018, at 8 PM EDT to submit their 2017 MIPS performance data. Eligible clinicans can submit their performance data using the new feature on the Quality Payment Program website .

Note: For groups that missed the March 16 CMS Web Interface data submission deadline, it’s not too late to submit your data through another mechanism. How to Get Started
Go to qpp.cms.gov and click on “sign in” on the top right side of the web page.

  • Log into the Quality Payment Program data submission feature using your Enterprise Identity Management (EIDM) credentialsuser name and password . If you don’t have an EIDM account, you’ll need to obtain one. Review this EIDM user guide and get started with the process as soon as possible. Currently, you should allow at least 5 business days for EIDM requests to be processed.
  • After logging in, the feature will connect you to the Taxpayer Identification Number (TIN) associated with your National Provider Identifier (NPI).
  • You’ll be able to report data either as an individual or as a group. Be sure to login and get familiar with the feature before you submit your data.

For questions or help using the data submission feature, contact the Quality Payment Program by email at qpp@cms.hhs.gov or toll free at 1-866-288-8292.

View the data submission fact sheet and this video to learn more about the Quality Payment Program data submission feature.

Posted 3/29/18


FDA Approves Nilotinib for Pediatric CML

March 23, 2018

On March 22, 2018, the U.S. Food and Drug Administration (FDA) approved nilotinib (Tasigna, Novartis Pharmaceuticals Corporation) for pediatric patients 1 year of age or older with newly diagnosed Philadelphia chromosome positive chronic myeloid leukemia (CML) in chronic phase (Ph+ CML-CP) or Ph+ CML-CP resistant or intolerant to prior tyrosine-kinase inhibitor (TKI) therapy. Read FDA announcement .

Posted 3/23/2018


USPSTF Issues Recommendation on Skin Cancer Prevention

March 21, 2018

The United States Preventive Services Task Force (USPSTF) released its final recommendation statement on behavioral counseling to prevent skin cancer. The task force recommends counseling young adults, adolescents, children, and parents of young children about minimizing exposure to ultraviolet (UV) radiation for persons aged 6 months to 24 years with fair skin types to reduce their risk of skin cancer. The USPSTF recommendation comes with B grade.

Read the recommendation here .

Read the full article published March 20, 2018, in the Journal of the American Medical Association .

Posted 3/21/18


CMS's OCM Team to Host May 3 Public Forum

March 20, 2018

The Centers for Medicare & Medicaid Services (CMS) has announced that the Oncology Care Model team will host a public forum for stakeholders on Thursday, May 3 from 1:00 PM – 4:00 PM EDT. All interested OCM stakeholders are invited to attend this public meeting, with the goal of hearing feedback about OCM. The meeting will include a brief introduction from the OCM team followed by discussion.

Registrants will be sent an agenda one week prior to the meeting that will include compiled topics submitted via the text field in the registration form.

Attendees may attend virtually or in-person at the Centers for Medicare & Medicaid Services Central Office located at 7500 Security Boulevard, Baltimore, Maryland 21244.

Registration for in-person attendance will close at 5:00 PM EDT on April 26, 2018 . Virtual registration will remain open until 1:00 PM EDT on Thursday May 3 . Virtual attendees will receive call-in information in the registration confirmation email.

Additional information, including access to the registration link, is available on the Oncology Care Model - Stakeholder Feedback Public Forum web page .

Posted 3/20/2018


FDA Approves Adcetris Combined with Chemotherapy for First-Line Treatment of Stage III or IV Classical Hodgkin Lymphoma

March 20, 2018

On March 20, 2018, the U.S. Food and Drug Administration (FDA) approved Adcetris (brentuximab vedotin) to treat adult patients with previously untreated stage III or IV classical Hodgkin lymphoma (cHL) in combination with chemotherapy. Read the FDA announcement .

Posted 3/20/2018


President's Cancer Panel Urges Collaboration to Better Align Drug Prices with Value

March 13, 2018

A report from the President's Cancer Panel released March 13 calls on stakeholders from all segments of oncology to join together to "maximize the value and affordability of cancer drug treatment" while continuing to support investment in research to propel future innovations.

"Cancer patients should not have to choose between paying for their medications or paying their mortgages. For so many, it is truly a matter of life and death," said Barbara K. Rimer, DrPH, chair of the President's Cancer Panel, in a statement. "This is a national imperative that will not be solved by any one sector working alone."

The report, Promoting Value, Affordability, and Innovation in Cancer Drug Treatment , urges action informed by three guiding principles:

  • Cancer drug prices should be aligned with their value to patients;
  • All patients should have affordable access to appropriate cancer drugs; and
  • Investments in science are essential to drive future innovation.

The President's Cancer Panel, established by the National Cancer Act of 1971, is an independent entity charged with monitoring the National Cancer Program and reporting to the President on any barriers to its execution. Learn more about the Panel's role and members .

Read the Executive Summary .
Read the Recommendations at a Glance .

Posted 3/13/18


ASTRO Issues Clinical Guideline for WBRT

March 13, 2018

The American Society for Radiation Oncology (ASTRO) today issued a new clinical guideline for the use of whole breast radiation therapy (WBRT) for breast cancer that expands the population of patients recommended to receive accelerated treatment known as hypofractionated therapy.

Reflecting current evidence from clinical trials and large cohort studies, the new guideline recommends hypofractionated WBI for breast cancer patients regardless of age, tumor stage, and whether they have received chemotherapy.

The guideline provides clinical guidance for dosing, planning and delivering whole breast irradiation (WBI) with or without an additional "boost" of radiation therapy to the tumor bed. Full recommendations and supporting evidence are provided in the guideline . Read the ASTRO press release .

Posted 3/13/18


Trump Administration Announces MyHealthEData Initiative

March 7, 2018

Centers for Medicare & Medicaid Services (CMS) Administrator Seema Verma has announced the administration's new MyHealthEData, an initiative that aims to give Americans more complete access to their healthcare data. She made the announcement in an address on March 6, 2018, at the Healthcare Information and Management Systems Society (HIMSS) Annual Conference in Las Vegas. The government-wide initiative is being led by the White House Office of American Innovation with participation from the Department of Health and Human Services, including CMS; Office of the National Coordinator for Health Information Technology (ONC); the National Institutes of Health; and the Department of Veterans Affairs.

As part of MyHealthEData announcement, CMS also announced that the agency intends to "overhaul" the EHR Incentive Programs to "refocus the programs on interoperability and to reduce the time and cost required" for providers to meet requirements.

In her remarks, Administrator Verma also described Medicare's Blue Button 2.0 - a tool that would allow Medicare beneficiaries to access and their personal health data in a "universal digital format."

As part of this initiative, the administration is also calling on healthcare insurers to follow suit and give patients access to their claims data in a digital format.

The administration is still developing a timeline for the initiative, Verma said in an interview with Bloomberg BNA . Read the CMS press release . Read the CMS fact sheet .

Posted 3/7/18


FDA Authorizes First Direct-to-Consumer Test For 3 BRCA Mutations

March 6, 2018

On March 6, 2018, the U.S. Food and Drug Administration (FDA) authorized the Personal Genome Service Genetic Health Risk (GHR) Report for BRCA1/BRCA2 (Selected Variants). It is the first direct-to-consumer (DTC) test to report on three specific BRCA1/BRCA2 breast cancer gene mutations that are most common in people of Ashkenazi (Eastern European) Jewish descent. These three mutations, however, are not the most common BRCA1/BRCA2 mutations in the general population.

The test analyzes DNA collected from a self-collected saliva sample, and the report describes if a woman is at increased risk of developing breast and ovarian cancer, and if a man is at increased risk of developing breast cancer or may be at increased risk of developing prostate cancer. The test only detects three out of more than 1,000 known BRCA mutations. This means a negative result does not rule out the possibility that an individual carries other BRCA mutations that increase cancer risk.

The FDA press release states:

"Consumers and healthcare professionals should not use the test results to determine any treatments, including anti-hormone therapies and prophylactic removal of the breasts or ovaries. Such decisions require confirmatory testing and genetic counseling. The test also does not provide information on a person’s overall risk of developing any type of cancer. The use of the test carries significant risks if individuals use the test results without consulting a physician or genetic counselor." Read the FDA announcement .

Posted 3/6/2018


FDA Approves Abemaciclib for HR+/HER2- Advanced Breast Cancer

February 27, 2018

On February 26, 2018, the U.S. Food and Drug Administration FDA) approved abemaciclib (Verzenio™, Eli Lilly and Company) in combination with an aromatase inhibitor as initial endocrine-based therapy for postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer. Read FDA announcement .

Posted 2/27/2018


FDA Approves Durvalumab for Stage III Unresectable NSCLC

February 20, 2018

On September 16, 2018, the U.S. Food and Drug Administration (FDA) approved Imfinzi (durvalumab) for the treatment of patients with stage III non-small cell lung cancer (NSCLC) whose tumors are not able to be surgically removed (unresectable) and whose cancer has not progressed after treatment with chemotherapy and radiation (chemoradiation).

Read the FDA announcement .

.


FDA Approves Erleada for Certain Prostate Cancer Patients

February 14, 2018

On February 14, 2018, the U.S. Food and Drug Administration (FDA) approved Erleada (apalutamide) for the treatment of patients with prostate cancer that has not spread (non-metastatic), but that continues to grow despite treatment with hormone therapy (castration-resistant). This is the first FDA-approved treatment for non-metastatic, castration-resistant prostate cancer.

Erleada works by blocking the effect of androgens, a type of hormone, on the tumor. These androgens, such as testosterone, can promote tumor growth.

The sponsor for Erleada is the first participant in the FDA’s recently-announced Clinical Data Summary Pilot Program , an effort to provide stakeholders with more usable information on the clinical evidence supporting drug product approvals and more transparency into the FDA’s decision-making process. Soon after approval, certain information from the clinical summary report will post with the Erleada entry on Drugs@FDA and on the new pilot program landing page . Read FDA press release .

Posted 2/14/2018


ASCO & NCCN Release Guidance on Management of Immunotherapy Side Effects

February 14, 2018

On February 14, 2018, the American Society of Clinical Oncology (ASCO) and the National Comprehensive Cancer Network (NCCN) jointly announced release of guidance on managing side effects of immunotherapy with immune checkpoint inhibitors. The organizations note that these guidelines pertain only to immune checkpoint inhibitors, not to other types of immunotherapy.

To date, several checkpoint inhibitor immunotherapies have been approved by the U.S. Food and Drug Administration (FDA) for treatment of a number of cancer types, including melanoma, Hodgkin lymphoma, and lung, liver, kidney, and bladder cancer. In the rapidly evolving cancer immunotherapy landscape, the number of agents, new indications, and combination therapies continues to grow.

In a joint news release, ASCO and NCCN briefly outline the guideline development process, which included convening multidisciplinary panels with representation from medical oncology, dermatology, gastroenterology, rheumatology, pulmonology, endocrinology, urology, neurology, hematology, emergency medicine, and nursing, as well as patient advocacy experts. The clinical recommendations were based on a systematic literature review and an informal consensus process.

"The Management of Immune-related Adverse Events in Patients Treated with Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline," was published online February 14, 2018, in the Journal of Clinical Oncology. Read the article .

NCCN Guidelines® for Management of Immunotherapy-Related Toxicities were published online at NCCN.org on February 14, 2018.

ASCO and NCCN welcome feedback on their guidelines from oncologists, practitioners, and patients through the ASCO Guidelines Wiki or via the NCCN submission form at NCCN.org .


Proceedings from NASEM Workshop on Weight Management & Exercise Across Cancer Continuum Available

February 12, 2018

The National Cancer Policy Forum of the National Academies of Sciences, Engineering, and Medicine (NASEM) has announced that the final Proceedings from its public workshop , Incorporating Weight Management and Physical Activity Throughout the Cancer Care Continuum are now available.

The workshop, held February 13-14, 2017, in Washington, D.C., highlighted the current evidence base, gaps in knowledge, and research needs on the associations among obesity, physical activity, weight management, and health outcomes for cancer survivors. Presentations and discussions also examined the effectiveness of interventions for promoting physical activity and weight management among people living with or beyond cancer, as well as opportunities and challenges for providing weight management and physical activity interventions to cancer survivors. Download proceedings .

Posted 2/12/18


White House Issues Report on Reforming Drug Pricing

February 12, 2018

A report from the White House Council of Economic Advisors released on February 9 asserts the need for major policy changes at the federal level in order to lower drug prices, including reforms impacting the FDA and changes to Medicare and Medicaid.

Read " Reforming Biopharmaceutical Pricing at Home and Abroad ."

Posted 2/12/2018


CMS to Host 2017 MIPS Submission Q & A Sessions

February 9, 2018

The Centers for Medicare & Medicaid Services (CMS) is hosting three “Office Hours” sessions on Merit-based Incentive Payment Systems (MIPS) submission over the next several weeks. CMS subject matter experts will answer commonly asked questions about the submission feature on qpp.cms.gov , and answer attendees’ questions live. Registrants will also be able to submit questions by email prior to the sessions.

View “Office Hours” topics and register below. Please note that Qualified Registries, Qualified Clinical Data Registries and Web Interface Reporters should use their support calls for data submission support.

February 14, 3:30-4:30 pm ET

Quality Payment Program Data Submission Office Hours: Individual Eligible Clinician and Group Submission

Register

February 28, 3-4 pm ET

Quality Payment Program Data Submission Office Hours: MIPS Quality Data Submission

March 14, 3-4 pm ET

Quality Payment Program Data Submission Office Hours: MIPS Attestation for Advancing Care Information and Improvement Activities

Space for these sessions is limited. Register now to secure your spot. The audio portion of the sessions will be broadcast through the web. You can listen to the presentation through your computer speakers.

For More Information

For step-by-step instructions on how to submit MIPS data, check out this video and fact sheet . Questions about your participation status or MIPS data submission? Contact the Quality Payment Program Service Center by
email: qpp@cms.hhs.gov .


MIPS Reporting Deadlines Coming Soon

February 8, 2018

Planning to submit data for the 2017 Merit-based Incentive Payment System (MIPS) Merit-based Incentive Payment System (MIPS) performance period? Deadlines are coming in March, and the Centers for Medicare & Medicaid Services (CMS) urges providers not to wait until the last minute to submit data.

The two key dates are:

  • March 16 at 8 pm ET for group reporting via the CMS web interface
  • March 31 for all other MIPS reporting, including via qpp.cms.gov

If you’re not sure if you are required to report for MIPS, enter your National Provider Identifier (NPI) in the MIPS Lookup Tool to find out whether you need to report. Additionally, if you know you are in a MIPS APM or Advanced APM, you can use the APM Lookup Tool .

Questions about your participation status or MIPS data submission? Contact the Quality Payment Program Service Center by:

  • Email: qpp@cms.hhs.gov
  • Phone: 1-866-288-8292 (TTY: 1-877-715-6222)

For more information and a quality reporting timeline, visit the Quality Payment Program website

Posted 2/8/18


FDA Approves Zytiga Plus Prednisone for Metastatic High-Risk Prostate Cancer

February 8, 2018

The Janssen Pharmaceutical Companies of Johnson & Johnson on February 8, 2018, announced U.S. Food and Drug Administration (FDA) approval of a new indication for Zytiga (abiraterone acetate) in combination with prednisone for the treatment of patients with metastatic high-risk castration-sensitive prostate cancer (CSPC).

Read Corporate Press Release
Posted 2/8/18


ASCO Reviews Commercial Clinical Pathways Landscape

February 8, 2018

The American Society of Clinical Oncology (ASCO) reviews six leading commercial oncology pathway vendors in "Oncology Clinical Pathways: Charting the Landscape of Pathway Providers." The article, published online February 7, 2018, in the Journal of Oncology Practice, " assesses six commercial clinical pathway vendors using ASCO's criteria for high-quality clinical pathways.

Read ASCO Press Release Access Article and Learn More
Posted 2/8/18


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