Learn how a pharmacy resident project supported the creation and implementation of an oral oncolytic collaborative practice agreement (CPA) that expanded pharmacist scope of practice, decreased turnaround time for processing prescriptions, improved provider satisfaction, and decreased patient prescription costs. Today, St. Luke’s Cancer Institute’s CPA allows pharmacists to sign prescriptions on behalf of providers for interventions such as renal or hepatic dose adjustments, dose rounding, renewal of prescription refills, adjustment for toxicities, dosing based on appropriate indication, and the ordering of laboratory tests and/or exams.